How to Watch Patriots vs Bills: Live Stream NFL Week 5, TV Channel

The New England Patriots will face the Buffalo Bills in Week 5 of the NFL season on Sunday at Highmark Stadium.

How to Watch Patriots vs Bills

• When: Sunday, October 5, 2025
• Time: 8:20 PM ET
• TV Channel: NBC
• Live Stream: Fubo (try for free)

The New England Patriots (2–2) arrive in Buffalo riding the momentum of their 42–13 win over the Panthers. Second‑year quarterback Drake Maye has shown promise, especially in recent weeks, and New England’s run game, led by Rhamondre Stevenson and TreVeyon Henderson, could try to exploit Buffalo’s weaker run defense. If they can take some pressure off Maye by running the ball effectively, it will give the Patriots the best chance to hang around in this one.

The Buffalo Bills (4–0) remain a dominant force, boasting the league’s second‑best offense. Josh Allen continues to look like the most complete offensive player in the sport, excelling both through the air and on the ground, and running back James Cook has been a touchdown machine. At home, with a whiteout crowd and in prime time, Buffalo is favored, but it would not be surprising to see them in a tough battle here, considering this is a divisional matchup.

This is a great NFL football matchup that you will not want to miss; make sure to tune in and catch all the action.

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